The St. Louis Cardinals and Miami Marlins meet in the middle game of their series on Wednesday, August 20, 2025, at loanDepot park. First pitch is scheduled for 6:40 PM ET. St. Louis (59–67) will start Andre Pallante (6–8, 4.39 ERA, 1.38 WHIP), while Miami (55–71) turns to former Cy Young winner Sandy Alcantara (7–10, 3.87 ERA, 1.21 WHIP). The Marlins are listed as –130 favorites, with the over/under set at 8.5 runs.
Team Analysis
St. Louis Cardinals
The Cardinals have struggled for consistency in 2025, falling out of the playoff race despite some solid individual performances. Paul Goldschmidt (.276 AVG, 24 HR, 82 RBI) continues to be a steady veteran presence, while Nolan Gorman (27 HR, 69 RBI) brings the power from the left side. Rookie shortstop Masyn Winn adds speed (23 stolen bases) and defense, but the lineup often struggles with situational hitting.
Pallante has provided innings but isn’t overpowering, striking out just 85 in 112 frames. His sinker generates ground balls, but when he misses his spots, he’s been vulnerable to right-handed power bats. The Cardinals’ bullpen remains middle-of-the-pack, with Ryan Helsley (24 saves, 3.21 ERA) closing games.
Miami Marlins
The Marlins have had a tough season, but Alcantara still gives them a legitimate ace every fifth day. He has logged 153 innings, tallying 142 strikeouts against 46 walks, and has looked sharper in recent outings.
Miami’s offense has been inconsistent, ranking near the bottom of the NL in runs scored. Jazz Chisholm Jr. (.243 AVG, 19 HR, 21 SB) provides excitement, while Josh Bell (16 HR, 62 RBI) has offered some stability in the middle of the order. Rookie Xavier Edwards has been a bright spot with his speed and on-base ability, but overall, Miami struggles to string together runs.
Key Matchups to Watch
- Alcantara vs Goldschmidt/Gorman – If Alcantara can neutralize St. Louis’ main power threats, Miami gains a big edge.
- Pallante vs Chisholm – Chisholm’s mix of power and speed is a dangerous test for a contact-first pitcher.
- Bullpen management – In a likely low-scoring game, one mistake late could decide it.
Prediction
Alcantara’s presence looms large in this matchup. While Miami’s lineup hasn’t produced much this season, they should scratch across enough against Pallante to back their ace. St. Louis needs its stars to deliver to have a chance, but on the road against Alcantara, it’s an uphill climb.
Final Score Prediction: Marlins 4, Cardinals 2
Best Bets
- Marlins Moneyline (–130) – Alcantara provides the clear pitching edge.
- Under 8.5 Runs – Two inconsistent offenses with solid pitching on both sides.
- Jazz Chisholm Anytime Hit + Stolen Base – A value prop given his aggressive baserunning.
