Overview
The San Diego Padres take on the Seattle Mariners in the second game of a three-game series on Tuesday, August 26, 2025, at 9:40 PM EDT at T-Mobile Park in Seattle, Washington. The sports card above confirms the game time and network (ROOT Sports NW). The Mariners won the series opener 5-4 on August 25, with Cal Raleigh’s homer and Andrés Muñoz’s save outpacing Ryan O’Hearn’s two-run shot. The Mariners lead the 2025 season series 3-1, including a 5-1 victory on May 16. This interleague matchup is crucial for the Padres to even the series and stay in the NL West race, and for the Mariners to bolster their AL West position. Fans seeking a winning edge can rely on this expert preview, featuring player insights, pitching matchups, and a prediction—unlock more game-changing tips with our exclusive MLB strategies now
Team Analysis
San Diego Padres
- 2025 Record (as of August 25): 74-57, 2nd in NL West
- Performance Overview: The Padres are 6-4 in their last 10 games, averaging 5.3 runs/game with a .260 batting average and a 3.88 ERA. Ryan O’Hearn’s .279 BA and Manny Machado’s 21 HRs lead the offense, but injuries to Jackson Merrill (OF, ankle), Michael King (SP, knee), Jhony Brito (RP, forearm), and Joe Musgrove (SP, elbow) test their depth.
- Strengths: Elite hitting (56-16 when out-hitting opponents) and a bolstered bullpen with Mason Miller (1.80 ERA).
- Weaknesses: Struggling road record (31-35) and a three-game road losing streak entering the series.
- Player to Watch: Ryan O’Hearn (1B) – His .279 BA, 16 HRs, 53 RBI, and .333 BA with a homer in his last 5 games make him a consistent threat.
Seattle Mariners
- 2025 Record (as of August 25): 70-61, 2nd in AL West
- Performance Overview: The Mariners are 3-7 in their last 10 games, averaging 3.9 runs/game with a .224 batting average and a 6.14 ERA. Cal Raleigh’s 49 HRs and Josh Naylor’s .282 BA drive the offense, but injuries to Trent Thornton (RP, Achilles), Logan Evans (RP, elbow), and Gregory Santos (RP, knee) weaken their bullpen.
- Strengths: Power hitting (186 HRs, 2nd in AL) and a strong home record (39-26).
- Weaknesses: Recent pitching struggles (6.14 ERA in last 10 games) and a 4-6 record against the spread.
- Player to Watch: Cal Raleigh (C) – His .247 BA, 49 HRs, 106 RBI, and 3-for-5 with two homers on August 24 make him a dangerous power hitter.
Head-to-Head Record
- Historical Context: The Mariners lead the 2025 season series 3-1, with wins including a 5-1 victory on May 16 (J.P. Crawford’s homer) and a 6-1 win on May 18 (Randy Arozarena’s homer). The Padres’ lone win was 6-3 on May 17, with Manny Machado’s homer. The Mariners hold a 68-63 all-time edge, with a 3-1 record in 2024.
- Recent Encounter: On August 25, the Mariners won 5-4, with Raleigh’s homer and Muñoz’s save overcoming O’Hearn’s two-run shot.
- Key Insight: The Mariners’ home power and pitching have outmatched the Padres, but San Diego’s deep lineup can exploit Seattle’s depleted bullpen.
Pitching Matchups Table
| Team | Pitcher | Record | ERA | Innings Pitched | Strikeouts | WHIP |
|---|---|---|---|---|---|---|
| Padres | Dylan Cease (RHP) | 12-9 | 3.46 | 171.0 | 202 | 1.14 |
| Mariners | Logan Gilbert (RHP) | 7-9 | 3.21 | 166.1 | 161 | 1.01 |
Strengths and Negatives of Pitchers
- Dylan Cease (Padres):
- Logan Gilbert (Mariners):
Key Players to Monitor
- San Diego Padres:
- Seattle Mariners:
Recent Performance
- San Diego Padres: At 74-57, the Padres are 6-4 in their last 10, scoring 53 runs while allowing 42, with their offense thriving but road pitching inconsistent.
- Seattle Mariners: At 70-61, the Mariners are 3-7 in their last 10, scoring 39 runs and allowing 54, with their pitching struggling but home offense showing power.
Critical Factors
- Venue: T-Mobile Park’s pitcher-friendly dimensions (3.85 park ERA) favor Cease and Gilbert’s strikeout-heavy styles, though Raleigh’s power can break through.
- Weather: Indoors, ensuring consistent conditions for a competitive game.
- Momentum: The Mariners’ home strength (39-26) and 3-1 series lead contrast with the Padres’ 6-4 run but three-game road losing streak.
- Betting Odds: Mariners favored at -130, with over/under at 8.0, reflecting their home edge and Gilbert’s pitching strength.
Prediction
The Seattle Mariners hold a slight edge in this matchup, driven by Logan Gilbert’s 3.21 ERA and elite home performance (2.80 ERA) compared to Dylan Cease’s 3.90 ERA on the road. The Padres’ deep lineup, led by O’Hearn and Machado, could exploit Gilbert’s struggles against them (4.50 ERA), but the Mariners’ power bats, sparked by Raleigh and Naylor, should capitalize on Cease’s road inconsistencies. Seattle’s bullpen, despite injuries, will likely hold the lead with Muñoz closing.
Final Prediction: Seattle Mariners win, 4-3. Raleigh hits a homer, and Gilbert pitches six strong innings.
Best Bets
- Moneyline: Seattle Mariners (-130) – Their home dominance and Gilbert’s edge make them a solid pick.
- Under 8.0 Runs – T-Mobile Park’s pitcher-friendly setup and both pitchers’ strikeout ability suggest a low-scoring game.
- Cal Raleigh to Record an RBI (+115) – His 49 HRs and red-hot form offer strong value against Cease.
This preview, based on the latest trends and stats as of August 25, 2025, delivers expert, trustworthy, and engaging content for MLB fans. Watch live on ROOT Sports NW, as noted in the sports card above.
