Milwaukee Brewers vs Chicago Cubs Prediction & Preview – August 20, 2025

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The NL Central rivals clash at Wrigley Field on Wednesday night as the Milwaukee Brewers take on the Chicago Cubs. First pitch is scheduled for 8:05 PM ET. Milwaukee sends electric young right-hander Jacob Misiorowski to the mound, while Chicago counters with the steady Colin Rea. With both clubs fighting for postseason positioning, this game carries plenty of weight.

Milwaukee Brewers Outlook

The Brewers are thrilled with the progress of Jacob Misiorowski, one of the most highly regarded arms in their system. Misiorowski brings a high-90s fastball and sharp breaking stuff, though command can be an occasional issue. If he’s in rhythm, he can dominate even seasoned hitters. Milwaukee’s lineup is powered by Christian Yelich’s resurgence, while William Contreras provides middle-of-the-order stability. If the Brewers can get early runs, Misiorowski has the stuff to make them stand up.

Chicago Cubs Outlook

The Cubs counter with Colin Rea, a dependable righty who thrives on location and keeping hitters off balance. While he lacks overpowering velocity, he can navigate lineups by inducing weak contact and working the corners. Offensively, Chicago relies heavily on Cody Bellinger and Nico Hoerner to set the tone. The Cubs have been streaky at the plate but tend to play well at Wrigley, where their home-field advantage often comes into play.

Key Matchup to Watch

Can Misiorowski handle the pressure of Wrigley under the lights? His strikeout ability is elite, but walks have been his weakness. On the other side, Rea must limit damage against Milwaukee’s hot bats in the middle of the lineup, especially Yelich and Contreras.

Prediction and Best Bets

This matchup feels like a contrast in pitching styles — raw power vs. steady precision. If Misiorowski commands his fastball, Milwaukee has the advantage. But if he falters, the Cubs’ lineup has enough experience to grind out at-bats and take control.

Best Bets:

  • Brewers Moneyline (if Misiorowski limits walks)
  • Under 9 runs (projected tight divisional game)

Final Score Prediction: Brewers 4, Cubs 3

Author

  • Corey Clarkson is a seasoned sports journalist and analyst with a passion for telling the stories behind the stats. With years of experience covering everything from the NFL playoffs to the World Cup, Corey’s insight bridges hard data with the human side of sports. His work dives deep into game strategy, player performance, and league trends—helping readers not just follow sports, but truly understand them. Whether it’s breaking down a crucial fourth-quarter play, analyzing a blockbuster trade, or exploring the culture around the game, Corey delivers content that informs, entertains, and sparks conversation.

    Corey has attended major sporting events across the world, interviewed professional athletes and coaches, and built a reputation for sharp, unbiased reporting. His goal is to bring fans closer to the action, whether they’re at the stadium, watching from home, or reading along.

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