Los Angeles Rams vs. Los Angeles Chargers – Preseason Week 2 Preview & Prediction

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Date: Saturday, August 16, 2025
Time: 7:00 PM ET
Location: SoFi Stadium, Inglewood, CA
TV:

The battle for Los Angeles takes center stage in Week 2 of the preseason as the Rams and Chargers square off at SoFi Stadium. Both teams are focused on evaluating depth, with starters likely to see minimal action. The Rams are looking to build on an efficient Week 1 showing, while the Chargers aim to bounce back from a sluggish offensive performance.

For more expert breakdowns and betting insights on every NFL matchup, visit our complete slate of NFL Picks.


Matchup Overview

The Chargers enter as a 3.5-point favorite with the total set at 36.5. Expect Los Angeles to lean on Easton Stick and rookie QB Levi Lewis, while the Rams are likely to rotate Stetson Bennett and Dresser Winn for most of the night.


Los Angeles Rams

On offense, the Rams executed a balanced attack in their opener, with Bennett showing good command of the passing game and RB Ronnie Rivers providing steady production on the ground. Defensively, the Rams applied consistent pressure, forcing hurried throws and limiting big gains. Special teams were effective, highlighted by a long punt return that set up a short touchdown drive. The Rams are 4-1 ATS in their last five preseason games.


Los Angeles Chargers

The Chargers’ offense struggled to sustain drives last week, though Stick’s mobility helped extend plays. Rookie RB Kimani Vidal brought burst to the ground game and will be a key factor in this matchup. Defensively, the Chargers showed strength in the trenches but gave up too many third-down conversions. Special teams coverage was sound, but the kicking game was shaky with one missed field goal. The Chargers are 5-2 ATS in their last seven preseason home contests.


Key Matchups to Watch

  1. Backup QBs and Game Management – Which signal-caller can avoid turnovers and control the tempo?
  2. RB Production – Rivers (Rams) vs. Vidal (Chargers) could decide field position battles.
  3. Third-Down Efficiency – Sustaining drives will be critical in a low-total game.

Betting Odds

  • Spread: Chargers -3.5 / Rams +3.5
  • Total (O/U): 36.5
  • Moneyline: Chargers -165 / Rams +140

(Odds via ESPN BET at time of writing — subject to change)


Prediction

This matchup should be competitive throughout, but the Chargers’ defensive front and running game may prove decisive in the second half. The Rams’ QB play could keep it close, but small mistakes may tip the scales.

Projected Final Score:
Chargers 19 – Rams 16

  • Total Points: 35 → ✅ Under 36.5
  • Margin: 3 points → ✅ Rams cover +3.5

Best Bets

  1. Rams +3.5 (-110) – Expect a close game decided late.
  2. Under 36.5 (-110) – Both offenses are likely to be conservative with backups in.
  3. First Half Under 18 (-110) – Slow early pace should keep scoring down.

For more expert predictions and analysis, check out our complete lineup of NFL Picks.

Author

  • Corey Clarkson is a seasoned sports journalist and analyst with a passion for telling the stories behind the stats. With years of experience covering everything from the NFL playoffs to the World Cup, Corey’s insight bridges hard data with the human side of sports. His work dives deep into game strategy, player performance, and league trends—helping readers not just follow sports, but truly understand them. Whether it’s breaking down a crucial fourth-quarter play, analyzing a blockbuster trade, or exploring the culture around the game, Corey delivers content that informs, entertains, and sparks conversation.

    Corey has attended major sporting events across the world, interviewed professional athletes and coaches, and built a reputation for sharp, unbiased reporting. His goal is to bring fans closer to the action, whether they’re at the stadium, watching from home, or reading along.

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